Synthesis of N-alkyl-Cα,α-dimethylglycine derivatives
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Synthesis, local anaesthetic and antiarrhythmic activities of N-alkyl derivatives of proline anilides.
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formation of the active alkylating species, i.e., the alkyldiazonium ion, has been described by Shapiro (3), and the alkylation of DNA has been described by Lawley and Thatcher (1). In order, however, to compare the effects of higher alkyl homologs on the properties of the DNA, the kinetics of formation of the active alkylating species are required. The TV-methyl, TV-ethyl,TV-propyl, and TV-but...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2014
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.p008.622